Irinotecan FDA Link Generic

A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.

Also Known As:

Camptosar; CPT 11; SN 38; 7-Ethyl-10-hydroxycamptothecin; CPT-11; Camptothecin-11; Irinotecan Hydrochloride; Irrinotecan; NK012 Compound; SN 38 11; SN-38; SN-38-11; 7 Ethyl 10 hydroxycamptothecin; CPT11; Camptothecin 11; SN3811; (1,4'-Bipiperidine)-1'-carboxylic acid, (4S)- 4,11- diethyl- 3,4,12,14- tetrahydro- 4- hydroxy- 3,14- dioxo- 1H- pyrano(3',4':6,7)indolizino(1,2- b)quinolin- 9- yl ester

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Camptothecin: 2033
    - Irinotecan: 7759

M R Redinbo Selected Research

M R Redinbo Research Topics

Disease

Drug/Important Bio-Agent (IBA)